Retinol is an important ingredient in many skin care products. It’s an antioxidant and can be used to treat mild acne, wrinkles, and hyperpigmentation. However, retinol has been shown to cause dryness, redness, peeling, and scaling skin. Increased sensitivity to the sun may also cause more severe reactions such as sunburns and blistering.
New research suggests that 7,8-DIHYDROXYFLAVONE, a natural antioxidant found in plants like hops and spices such as cinnamon, cumin, oregano, thyme, and turmeric may be a good alternative to retinol. This study looked at the effects of 7-8-dihydroxyflavone on skin inflammation in mice with contact dermatitis (a type of eczema), as well as how it improved lipid peroxidation levels in the skin. Findings demonstrated that 7-8-dihydroxyflavone significantly reduced.
What Is 7-8-Dihydroxyflavone?
7-8-dihydroxyflavone is a flavonoid that can be found in plants like hops and spices like cinnamon, cumin, oregano, thyme, and turmeric. It’s believed to be an antioxidant that can reduce inflammation and oxidative stress.
7-8-Dihydroxyflavone And Skin Inflammation
New research suggests that 7-8-dihydroxyflavone, a natural antioxidant found in plants like hops and spices such as cinnamon, cumin, oregano, thyme, and turmeric may be a good alternative to retinol.
This study looked at the effects of 7-8-dihydroxyflavone on skin inflammation in mice with contact dermatitis (a type of eczema), as well as how it improved lipid peroxidation levels in the skin. Findings demonstrated that 7-8-dihydroxyflavone significantly reduced sebum production and enhanced lipid peroxidation levels.
It also decreased the number of mast cells present in the skin (which are known to cause inflammation). In addition, it decreased superoxide dismutase activity and increased glutathione levels.
7-8-Dihydroxyflavone was also shown to decrease cell death. These promising findings suggest that 7-8-dihyhdroxyflavone could be a valuable skin care ingredient for those who want an alternative to retinol with fewer side effects.
7-8-Dihydroxyflavone And Lipid Peroxidation
The study found that 7-8-dihydroxyflavone reduced lipid peroxidation levels in the skin, which is a process that occurs when free radicals cause deterioration of cell membranes. By preventing lipid peroxidation, 7-8-DHF prevented the oxidation of unsaturated fatty acids and lipids in the cells.
In addition, 7-8-DHF had a protective effect on mouse skin from oxidative damage, inflammation, and contact dermatitis. This antioxidant also decreased oxidative stress and lipid peroxidation levels in both the epidermis and dermis. These beneficial effects were seen even after a single dose of 7-8-DHF.
7-8-DHF was safe for use in this study at a dose of 1mg/kg mice for 10 days, so there may be potential for its use as a topical antioxidant treatment for eczema or other inflammatory skin conditions. In this study, it was shown to be as effective as retinol without causing any adverse reactions.
Effects On Contact Dermatitis
The results of this study suggest that 7,8-DIHYDROXYFLAVONE may be a better alternative to retinol, as it does not cause redness and scaling skin. Furthermore, it improves lipid peroxidation levels in the skin.
This could be a good option for people who are sensitive to retinol, or those who want to avoid it due to its side effects. It also has the added benefit of being an antioxidant. I would consider using 7-8-dihydroxyflavone in addition to my retinol skincare routine.